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KMID : 1009020160140020221
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Clinical Psychopharmacology and Neuroscience
2016 Volume.14 No. 2 p.221 ~ p.225
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Acute Dystonia Following a Switch in Treatment from Atomoxetine to Low-dose Aripiprazole
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Omer Ba?ay
Burge Kabukcu Basay
Onder Ozturk
Zeki Yuncu
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Abstract
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The present report describes the cases of a 17-year-old male patient and a 13-year-old female patient who developed acute dystonia following the administration of low-dose aripiprazole (5 mg/day) after the cessation of atomoxetine treatment. Although aripiprazole-induced dystonia has been previously reported in the literature, it is rare, and most of these cases were associated with doses higher than 5 mg/day. Furthermore, both of the patients in the present study discontinued atomoxetine prior to the initiation of aripiprazole treatment; thus, this report also discussed the possible mechanisms underlying the manifestation of dystonia from the perspective of neurotransmitter activity.
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KEYWORD
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Aripiprazole, Atomoxetine, Dystonia
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